Buy Cialis Online

At present, for the prevention and treatment of erectile dysfunction are most often used such drugs as Viagra (active ingredient – sildenafil citrate) and Cialis (active ingredient – Tadalafil).

First in the world pharmaceutical market appeared Viagra 1998, Cialis on sale in 2003.

The mechanism of action of both drugs is the same and by blocking the enzyme phosphodiesterase type 5 (PDE-5), which in turn cleaves the enzyme cyclic guanosine monophosphate, which is responsible for the vascular component of penile erection. Men with erectile dysfunction, reduced levels of cyclic guanosine monophosphate and always sufficient to ensure a strong full erection.

In order to improve the content of cyclic guanosine monophosphate was used a simple but nevertheless long been non-obvious method, by blocking an enzyme that breaks down cyclic guanosine monophosphate.

Data on the pharmacokinetics of drugs Viagra and Cialis indicate greater effectiveness of Cialis. The half-life of sildenafil (Viagra active ingredient) is shorter and is only 3-5 hours, depending on the dose, while at the Cialis – 17.5  hours. Time saving and effective activity to achieve an erection Viagra is an average of 4 hours for Cialis – 24-36 hours.

Side effects of Viagra and Cialis are similar on average. This dizziness, headache, diarrhea, nausea, nasal congestion, feeling a rush of blood to the head. Just Cialis has a number of side rarely expressed effects due to back pain, abdominal and joint pain.

All unwanted side effects of both drugs coming, usually occur in mild to moderate form. But with continued treatment of erectile dysfunction drug Cialis side effects have less pronounced and go at all.

Both drugs absolutely contraindicated for men, constantly receiving containing nitrato drugs (nitroglycerin in all its forms and its analogues).

Since Viagra went on the market before, it is more understood.

In 2002, American toxicologist G. Millman published in the journal “Annals of Pharmacotherapy” the results of scientific research about the side effects of Viagra. Patients taking Viagra reported dizziness, disorientation, amnesia, 22 people out of 270 was attributable to the emergence of Viagra aggression, 13 – to provoke violence, the drug caused a six man “a strong desire to kill.” Side effects of sildenafil were manifested by chronic administration of the maximum therapeutic doses (150 mg daily).

Other sources independently informed about the incompatibility of Viagra with alcohol. Mutual potentiation of the hypotensive effect of Viagra and alcohol cost the lives of some pensioners do not comply with the ban on alcohol intake. Viagra and alcohol is a big strain on the heart. Also, for maximum efficiency, should only take Viagra on an empty stomach.

Numerous clinical studies the efficacy and safety of Cialis pay attention to the lack of restrictions on the drug with fatty food and alcohol in small quantities, which significantly increases the loyalty of patients and meet the requirements of some of them to normal life.

Thus, the analysis of the available scientific and clinical data on the properties and the effect of Viagra and Cialis can opt for Cialis.